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Fluorous Technologies fluorous-based carbohydrate microarrays
Fluorous Based Carbohydrate Microarrays, supplied by Fluorous Technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/fluorous+microarrays/fluorous+based+carbohydrate+microarrays/pm34923822-331-10-12
Average 90 stars, based on 1 article reviews
fluorous-based carbohydrate microarrays - by Bioz Stars, 2026-09
90/100 stars

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Binding Assay:

Article Title: Literature Search and Review
Article Snippet: Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets.. The biological consequences of multi-kinase activity are poorly defined, and an important step toward understanding the relationship among selectivity, efficacy, and safety is the exploration of how inhibitors interact with the human kinome.. We present interaction maps for 38 kinase inhibitors across a panel of 317 kinases representing 50% of the predicted human protein kinome.

Article Title: Methods for the synthesis and detection of perfluorinated small molecules as tools for chemical biology
Article Snippet: .. These works have explicitly demonstrated minimal non-specific binding on fluorous microarrays.145,146 Fluorous-tagged DNA can be used for micropatterning in a reversible manner through five cycles of immobilization and removal.145 Peptides can be presented for protease screening; careful design of the linker between the peptide and the fluorous tag leads to negligible enzyme inhibition.147 Similarly, small molecules have been displayed to identify histone deacetylase inhibitors.148 Crude cell-lysates containing enzymes of interest can be assessed by treating fluorous- tagged enzyme substrates immobilized on a fluorous surface. ..

Analogues:

Article Title: Literature Search and Review
Article Snippet: Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets.. The biological consequences of multi-kinase activity are poorly defined, and an important step toward understanding the relationship among selectivity, efficacy, and safety is the exploration of how inhibitors interact with the human kinome.. We present interaction maps for 38 kinase inhibitors across a panel of 317 kinases representing 50% of the predicted human protein kinome.

Inhibition:

Article Title: Methods for the synthesis and detection of perfluorinated small molecules as tools for chemical biology
Article Snippet: .. These works have explicitly demonstrated minimal non-specific binding on fluorous microarrays.145,146 Fluorous-tagged DNA can be used for micropatterning in a reversible manner through five cycles of immobilization and removal.145 Peptides can be presented for protease screening; careful design of the linker between the peptide and the fluorous tag leads to negligible enzyme inhibition.147 Similarly, small molecules have been displayed to identify histone deacetylase inhibitors.148 Crude cell-lysates containing enzymes of interest can be assessed by treating fluorous- tagged enzyme substrates immobilized on a fluorous surface. ..

Histone Deacetylase Assay:

Article Title: Methods for the synthesis and detection of perfluorinated small molecules as tools for chemical biology
Article Snippet: .. These works have explicitly demonstrated minimal non-specific binding on fluorous microarrays.145,146 Fluorous-tagged DNA can be used for micropatterning in a reversible manner through five cycles of immobilization and removal.145 Peptides can be presented for protease screening; careful design of the linker between the peptide and the fluorous tag leads to negligible enzyme inhibition.147 Similarly, small molecules have been displayed to identify histone deacetylase inhibitors.148 Crude cell-lysates containing enzymes of interest can be assessed by treating fluorous- tagged enzyme substrates immobilized on a fluorous surface. ..



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